Finalmente conseguir resolver a porcaria de erro que não deixava rodar um simples window.open!
foi tão foda de achar a solução que resolvi compartilhar.
Download/run the appropriate, newly-updated script(s) by IE MVP Kai Schaetzl:
http://iefaq.info/index.php?action=artikel&cat=42&id=133&artlang=en
Tip: The file named ie8-rereg.all.zip contains all three (3) scripts below.
If you have a Win7 32-bit computer:
• Close all open applications (i.e., anything with an icon on the taskbar) then Run the script named ie8-rereg.cmd & reboot.
If you have a Win7 64-bit computer:
• Close all open applications (i.e., anything with an icon on the taskbar) then Run the script named ie8-rereg.32on64.cmd to correct the problem in IE8 32-bit & reboot.
• Close all open applications (i.e., anything with an icon on the taskbar) then Run the script named ie8-rereg.64on64.cmd to correct the problem in IE8 64-bit & reboot.
NB: If the above is your fix, either a Norton or McAfee application is installed or one had been installed. YMMV.
Fonte: social.answers.microsoft.com